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News That Matters

27/01/2023 ---- 02/02/2023

The territorial dispute between Jews and Palestinians revolves around the control and ownership of land, particularly in the West Bank and East Jerusalem. Jews have claimed the land as their ancestral homeland and see it as their right to live there. Palestinians, on the other hand, see the West Bank and East Jerusalem as part of a future Palestinian state and argue that the presence of Israeli settlements is illegal under international law. The conflict over the territory has been ongoing for decades, with both sides claiming rights to the land and engaging in acts of violence and conflict to support their claims. Efforts to resolve the dispute and find a peaceful solution have been made through negotiations and peace processes. Still, a final resolution has yet to be reached. Last week, within a few days, there were reciprocal attacks and acts of violence between Palestinians and Israelis. It all started Thursday, January 26, with an Israeli army military operation in the West Bank, in the Jenin refugee camp, in which 10 Palestinians were killed, which was followed first by an exchange of missiles and rockets between Israel and the Gaza Strip, and then between Friday and Saturday two attacks by Palestinians in East Jerusalem. In the first, the most serious, a 21-year-old man killed seven people while leaving a synagogue: not so many people have been killed in a single attack in Jerusalem for 15 years.

The origin of this conflict has old roots. Jerusalem's Old City is divided into four quarters: Muslim, Christian, Jewish, and Armenian. The Eastern part of the Old City is called the "East Jerusalem" and holds significant religious and cultural importance for Jews, Muslims, and Christians. In the 7th century, Jerusalem was conquered by Arab forces and became a cultural centre for Islam. The city remained under Muslim control until the First Crusade in 1099 when Christian knights captured the city and established the Kingdom of Jerusalem. In 1187, the city was retaken by Muslim warrior Saladin, who became a hero in Islamic history. During Ottoman rule, Jerusalem's East became a predominantly Muslim neighbourhood. In 1917, British forces captured the city during World War I and established the British Mandate in Palestine. The conflict between Jews and Arabs over control of Palestine and the city of Jerusalem escalated in the 20th century, leading to the 1948 Arab-Israeli War and the establishment of Israel. In the 1967 Six-Day War, Israel captured and reunified the Old City of Jerusalem. Today, the Old City is a major tourist destination and pilgrimage site for people of different faiths, with the Temple Mount and the Western Wall, both revered by Jews, the Church of the Holy Sepulchre, one of Christianity's holiest sites, and the Al-Aqsa Mosque, a primary Islamic site, located in Jerusalem's East.

Since December 2022, a new government by Benjamin Netanyahu has been formed, and tensions between Israelis and Palestinians have grown significantly. The government is the most right-end in Israel's history. It includes ministers, such as Itamar Ben-Gvir, holding a strong nationalist ideology. Itamar Ben-Gvir is known for his controversial views on issues such as Israeli settlements in the West Bank, Palestinian statehood, and the treatment of Arab Israelis. He is a vocal opponent of the peace process. He has been associated with several acts of extremism and incitement, leading many to view him as a divisive figure in Israeli politics. The international community is notoriously divided over the issue of Israeli control of East Jerusalem. Some countries recognize Israel's sovereignty over the city, while others do not. The issue has led to debates and negotiations, with some countries supporting Israel and others supporting the Palestinians. Despite international efforts to resolve the conflict, the situation remains unresolved, and tensions continue to simmer in Jerusalem and the wider region.

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Pathogenic fungi are common fungi that cause disease in humans or other organisms. Approximately 300 fungi are pathogenic to humans, mainly to immune-compromised subjects such as HIV-infected or organ-transplanted people. Among pathogenic fungi, we find Candida, Aspergillus, and Cryptococcus, which can cause diseases such as vaginal candidiasis, fungal nail infection, aspergillosis and cryptococcus infection. Healthy people with a functional immune system usually don't have to worry about these diseases since symptoms disappear without treatment.

However, all that may be about to change: a new study by a team of scientists at Duke University School of Medicine and published on January 20 in the Proceedings of the National Academy of Sciences finds that raised temperatures can cause a pathogenic fungus - known as Cryptococcus deneoformans - to turn its adaptative responses. Briefly, high temperatures increase its genetic changes, some of which may lead to higher heat resistance and more significant disease-causing potential. Specifically, higher heat induces changes in a specific region of its DNA called jumping genes, thus allowing the fungus to adapt to extreme environmental conditions (and, therefore, to increased resilience in general). The study suggests that high temperatures may contribute to the evolution of pathogenic traits in fungi during infection. Similar mechanisms in various fungi species may evolve faster than expected due to rising global temperatures.

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Body hair is a defining mammalian characteristic, but several mammals, such as whales, naked mole rats and humans, have notably less hair. The evolutionary mechanism of body hair loss is well understood: some animals do not have hair on their entire body because it is not necessary for survival or reproduction. For example, certain marine mammals, such as dolphins and whales, have little to no body hair because it would harm their ability to swim efficiently. Similarly, some animals that live in hot environments may have less hair as it helps them to regulate their body temperature. It is believed that also humans have evolved to have hairless skin because it allows them to regulate their body temperature. Humans have evolved to have efficient sweat glands, which help them to cool down by sweating. Fur can trap heat and make it difficult for an organism to cool down, which would be detrimental in hot environments. Additionally, the development of clothing and other body coverings has also made fur unnecessary for human survival.

Even though all these facts are known and understood, the genetic mechanism of body hair growth is still a mystery. A recent study by scientists from the University of Utah, published in the journal Elife, unlocked the mystery by examining how hairlessness evolved in different species at different times. By comparing the human genetic code with those of 62 other mammals, including elephants, manatees and chimpanzees, they managed to identify the genes involved in the expression of body hair. To find the genetic basis of reduced hair quantity, the scientists compared more than 19,000 genes and, through cutting-edge methods, narrowed their focus to those linked to keeping or losing body hair. Many genes linked to hair growth contain instructions for making the protein keratin, which forms hair, nails and the skin’s outer layer. The authors found that although the genes for a complete covering of body hair remain in our genetic code, they have been muted and lost their function.

This study marks the first time genetic mechanisms behind various hair traits have been studied in such a diverse group of mammals. Using a novel computational approach, which allows for estimating the genome evolution rate, the research team was able to identify genes and processes that no one knew to be involved in hair growth or hairlessness in mammals. This study and the method used may pave the way for finding out how to treat genetic conditions such as baldness.

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