NUNZIUM

News That Matters

21/12/2022 ---- 23/12/2022

PAST MONHT

month -1

HOMEPAGE

go_today

NEXT MONTH

month +1
23.12.2022
THEME: HEALTH

FDA approved the first monoclonal antibody drug for the treatment of COVID-19 hospitalized patients

The FDA has approved Tocilizumab - also known as Actemra and commercialized by Roche Genentech - for treating hospitalized COVID-19 patients. The treatment is for individuals who receive corticosteroids and require supplemental oxygen, non-invasive or invasive mechanical ventilation or oxygenation. Tocilizumab is the first FDA-approved monoclonal antibody treatment for COVID-19, recommended for use as a single intravenous injection. Scientists evaluated Tocilizumab for the treatment of COVID-19 in 4 studies in more than 5500 individuals who were hospitalized. The studies showed that Tocilizumab may improve outcomes in individuals receiving corticosteroids and requiring supplemental oxygen or breathing support. There were no new warnings or precautions related to Tocilizumab noted in the trials, with the most common adverse events being anxiety, constipation, diarrhoea, hypertension, insomnia, nausea, and urinary tract infection. More than one million people hospitalized with COVID-19 have been treated with Actemra worldwide since the pandemic's beginning. Tocilizumab has been approved for use for COVID-19 in the United States, European Union, Japan, the United Kingdom, New Zealand, Russia, and Brazil. It is also provisionally approved in Australia and authorized for emergency use in Ghana, Mexico, and Korea for individuals hospitalized with severe or critical COVID-19. The World Health Organization has also recommended and prequalified the drug.

READ MORE
21.12.2022
THEME: ENVIRONMENT

At COP15 in Montreal, nations agreed on four goals and 23 targets to protect biodiversity

Earlier this year, the environmental issues have been growing, ranging from devastating floods to extreme heat and drought in the northern hemisphere. The preservation of biodiversity is crucial to sustaining human life on Earth. On this topic, countries have reunited in Montreal, Canada, from December 7 to 19 at the UN COP15 conference. The conference was presided over by China. The premises of this meeting called for prompt action to preserve biodiversity: the latest WWF's Living Planet Report warned that global wildlife populations declined by 69% on average from 1970 to 2018. The accelerating loss of nature has already impacted human well-being and economies. Healthy ecosystems also play indispensable roles in tackling climate change, and biodiversity loss weakens our resilience. In response, nations agreed on four goals and 23 targets to protect biodiversity. The four goals are: (1) to maintain genetic biodiversity, increase the natural ecosystem's areas and reduce extinction rate and risk tenfold (2) to support the restoration and maintenance of biodiversity (3) to share the monetary and non-monetary benefits equitably from utilizing genetic resources, including with indigenous populations and local communities (4) to guarantee adequate means of implementation, including financial resources, capacity-building, and technical and scientific cooperation. A few of the 23 targets for 2030 supporting these goals are undoubtedly relevant. It is agreed to reach the conservation of at least 30% of the world's lands, inland waters, coastal areas and oceans (today, only 17% and 10% of the world's terrestrial and marine areas are under protection). Further, a target mentions reducing the loss of areas of high biodiversity importance to near zero, including ecosystems of high ecological integrity. It is also agreed to cut global food waste in half and reduce overconsumption and waste generation. Financial targets also mentioned phasing out subsidies that harm biodiversity by at least $500 billion per year while mobilizing by 2030 at least $200 billion per year in domestic and international biodiversity-related funding from all sources – public and private. Although all the targets agreed upon in Montreal are impressive, it is fair to question if they will be achieved. In fact, in 2002, nations committed "to achieve by 2010 a significant reduction of the current rate of biodiversity loss". They failed. In 2010 they met in Japan and agreed on a new plan, which included the 20 Aichi Targets. But not one of these targets was fully satisfied by the 2020 deadline. It is worth noting that, being these targets non-binding by law, they are rather guidelines to support objectives. Despite the ambition demonstrated at COP15 leaving hope, it remains true that just earlier this year, a monumental occasion to protect biodiversity failed miserably. At the end of last August, after 15 years of negotiations, nations could not agree on a binding pact to preserve Earth's oceans' biodiversity in another UN meeting in New York - probably the biggest of the lost occasions to preserve our marine ecosystems.

READ MORE

PAST MONTH

month -1

HOMEPAGE

go_today

NEXT MONTH

month +1